Characterization of Egyptian Moringa Peregrine Seed Oil And Its Bioactivities
Author(s)
Hanaa H. Abd El Baky , Gamal S. El-Baroty ,
Download Full PDF Pages: 98-108 | Views: 374 | Downloads: 94 | DOI: 10.5281/zenodo.3412650
Abstract
The seed oil of Egyptian Moringa peregrina (Forssk) was extracted with a mixture of dichloromethane/methanol (1:1, v/v). The oil was examined with respect to physicochemical properties, unsaponifiable (UnSap) and fatty acids profiles, tochopherols and phenolic contents, anticancer and antioxidant activities. Moringa oil (MO) showed a better overall quality, its acid, peroxide, iodine, saponification values were 0.02 mg KOH/g oil, 0.01 meq O2/kg oil, 67 I2 g/100 g oil and 177 mg KOH/g. The Un-Sap of MO was found to contain high amounts of hydrocarbon fraction C12 to C32 and phytoesterol fractions were found rich in campesteol, clerosterol and sitosterol compounds. The major fatty acids were identified as oleic (C18:1 9, 65.36%) and linoleic (C18:3 6, 15.32%). Tocopherols and phenolic in oil accounted for 20.35 and 48.31 mg/100 g. The Moringa oil showed high growth inhibition against three human cancer cell lines, breast adenocarcinoma (MCF-7), hepatocellular carcinoma (HepG2), and colon carcinoma (HCT-116), with IC50 values of 2.92, 9.40 and 9.48 µg/ml, respectively. The MO showed remarkable antioxidant activity, compared with that of commonly used antioxidants (-tocopherol, BHT and BHA) as determined by five antioxidant assays (includes, free radical scavenging of DPPH, ABTS, .OH, anion-scavenging capability and reducing power. These results strongly suggested its potential use MO as non-conventional seed crop for high quality oil and as candidate in the area of natural anticancer and antioxidant compounds.
Keywords
Moringa peregrina, seed oil, anticancer, fatty acid, antioxidant activity.
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